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1

Dissemination of Orientia tsutsugamushi, a Causative Agent of Scrub Typhus, and Immunological Responses in the Humanized DRAGA Mouse

Jiang, Le, Morris, Erin K., Aguilera-Olvera, Rodrigo, Zhang, Zhiwen, Chan, Teik-Chye, Shashikumar, Soumya, Chao, Chien-Chung, Casares, Sofia A., Ching, Wei-Mei

Journal:

Frontiers in Immunology

Year:

2018

Language:

english

File:

PDF, 2.15 MB

english, 2018

2

Immune evasion by malaria parasites: a challenge for vaccine development

Sofia Casares, Thomas L Richie

Journal:

Current Opinion in Immunology

Year:

2009

Language:

english

File:

PDF, 1.03 MB

english, 2009

3

Differential partitioning and trafficking of GM gangliosides and cholesterol-rich lipid rafts in thymic and splenic CD4 T cells

Teodor-D. Brumeanu, Anca Preda-Pais, Cristina Stoica, Constantin Bona, Sofia Casares

Journal:

Molecular Immunology

Year:

2007

Language:

english

File:

PDF, 576 KB

english, 2007

4

Down-regulation of autoreactive T-cells by HMG CoA reductase inhibitors

Teodor-D. Brumeanu, Robert Goldstein, Sofia Casares

Journal:

Clinical Immunology

Year:

2006

Language:

english

File:

PDF, 314 KB

english, 2006

5

Kounis Syndrome During Anesthesia

de la Fuente Tornero, Elena, Vega Castro, Arantza, Álvarez de Sierra Hernández, Pedro, Balaguer Recena, Javier, Zaragoza Casares, Sofía Carmen, Serrano Baylin, Francisco Miguel, Gallardo Culebradas, P

Journal:

A & A Case Reports

Year:

2017

Language:

english

File:

PDF, 502 KB

english, 2017

6

Towards development of T-cell vaccines

Constantin A. Bona, Sofia Casares, Teodor-D. Brumeanu

Journal:

Immunology Today

Year:

1998

Language:

english

File:

PDF, 965 KB

english, 1998

7

Efficacy of clonal deletion vs. anergy of self-reactive CD4 T-cells for the prevention and reversal of autoimmune diabetes

Anca Preda-Pais, Alexandru C. Stan, Sofia Casares, Constantin Bona, Teodor-D. Brumeanu

Journal:

Journal of Autoimmunity

Year:

2005

Language:

english

File:

PDF, 643 KB

english, 2005

8

Presentation of a viral peptide assembled on the carbohydrate moieties of immunoglobulin does not require processing

Teodor-D. Brumeanu, Sofia Casares, Philip Dehazya, Simona Bot, Constantin A. Bona

Journal:

European Journal of Immunology

Year:

1997

Language:

english

File:

PDF, 1.83 MB

english, 1997

9

Foreign Peptides Expressed in Engineered Chimeric Self Molecules

Casares, Sofia, Bot, Adrian, Brumeanu, Teodor-Doru, Bona, Constantin A.

Journal:

Biotechnology and Genetic Engineering Reviews

Year:

1998

Language:

english

File:

PDF, 2.79 MB

english, 1998

10

A Peptide-Major Histocompatibility Complex II Chimera Favors Survival of Pancreatic β-Ιslets Grafted in Type 1 Diabetic Mice

Casares, Sofia, Lin, Marvin, Zhang, Nan, Teijaro, John R., Stoica, Cristina, McEvoy, Robert, Farber, Donna L., Bona, Constantin, Brumeanu, Teodor D.

Journal:

Transplantation Journal

Year:

2008

Language:

english

File:

PDF, 635 KB

english, 2008

11

RNA degradation precedes DNA cleavage in autoreactive CD4 T cells suppressed by calicheamicin γ1

Sunil Thomas, Anca Preda-Pais, Sofia Casares, Teodor-D. Brumeanu

Journal:

International Immunopharmacology

Year:

2004

Language:

english

File:

PDF, 234 KB

english, 2004

12

Protective Immunity Elicited by Vaccination with DNA Encoding for a B Cell and a T Cell Epitope of the A/PR/8/34 Influenza Virus

CASARES, SOFIA, BRUMEANU, TEODOR-DORU, BOT, ADRIAN, BONA, CONSTANTIN A.

Journal:

Viral Immunology

Year:

1997

Language:

english

File:

PDF, 1.78 MB

english, 1997

13

Tracking Human Immunodeficiency Virus-1 Infection in the Humanized DRAG Mouse Model

Kim, Jiae, Peachman, Kristina K., Jobe, Ousman, Morrison, Elaine B., Allam, Atef, Jagodzinski, Linda, Casares, Sofia A., Rao, Mangala

Journal:

Frontiers in Immunology

Year:

2017

Language:

english

File:

PDF, 554 KB

english, 2017

14

10.1038/84404

Casares, Sofia, Stan, Alexandru C., Bona, Constantin A., Brumeanu, Teodor- D.

Journal:

Nature Biotechnology

Year:

2001

Language:

english

File:

PDF, 752 KB

english, 2001

15

Humanized HLA-DR4.RagKO.IL2RγcKO.NOD (DRAG) mice sustain the complex vertebrate life cycle of Plasmodium falciparum malaria

Wijayalath, Wathsala, Majji, Sai, Villasante, Eileen F, Brumeanu, Teodor D, Richie, Thomas L, Casares, Sofia

Journal:

Malaria Journal

Year:

2014

Language:

english

File:

PDF, 4.36 MB

english, 2014

16

CpG motifs of DNA vaccines induce the expression of chemokines and MHC class II molecules on myocytes

Alexandru C. Stan, Sofia Casares, Teodor-Doru Brumeanu, Dennis M. Klinman, Constantin A. Bona

Journal:

European Journal of Immunology

Year:

2001

Language:

english

File:

PDF, 475 KB

english, 2001

17

Reversal of type 1 diabetes by a new MHC II-peptide chimera: “Single-epitope-mediated suppression” to stabilize a polyclonal autoimmune T-cell process

Marvin Lin, Cristina Stoica-Nazarov, Jacqueline Surls, Margaret Kehl, Constantin Bona, Cara Olsen, Teodor D. Brumeanu, Sofia Casares

Journal:

European Journal of Immunology

Year:

2010

Language:

english

File:

PDF, 637 KB

english, 2010

18

Down-regulation of diabetogenic CD4+ T cells by a soluble dimeric peptide–MHC class II chimera

Casares, Sofia, Hurtado, Alicia, McEvoy, Robert C., Sarukhan, Adelaida, von Boehmer, Harald, Brumeanu, Teodor-Doru

Journal:

Nature Immunology

Year:

2002

Language:

english

File:

PDF, 1.41 MB

english, 2002

19

Constantin A. Bona, M.D., Ph.D.

Bot, Adrian, Bailey, Celeste, Brumeanu, Teodor, Casares, Sofia, Kuppuswamy, Kasturi, Zaghouani, Habib

Journal:

International Reviews Of Immunology

Year:

2016

Language:

english

File:

PDF, 377 KB

english, 2016

20

Humanized HLA-DR4 Mice Fed with the Protozoan Pathogen of Oysters Perkinsus Marinus (Dermo) Do Not Develop Noticeable Pathology but Elicit Systemic Immunity

Wijayalath, Wathsala, Majji, Sai, Kleschenko, Yuliya, Pow-Sang, Luis, Brumeanu, Teodor D., Villasante, Eileen Franke, Vasta, Gerardo R., Fernández-Robledo, José-Antonio, Casares, Sofia, Moser, Muriel

Journal:

Year:

2014

Language:

english

File:

PDF, 1.85 MB

english, 2014

21

Characterization of mutated protein encoded by partially duplicated fibrillin-1 gene in tight skin (TSK) mice

Shinichiro Saito, Hiroyuki Nishimura, Teodor-D Brumeanu, Sofia Casares, Alexandru C. Stan, Tasuku Honjo, Constantin A. Bona

Journal:

Molecular Immunology

Year:

1999

Language:

english

File:

PDF, 221 KB

english, 1999

22

Isolation of human lymphocytes with high yield and viability from the gastrointestinal and female reproductive tract of a humanized DRAG mouse

Allam, Atef, Peachman, Kristina K., Aguilera-Olvera, Rodrigo, Casares, Sofia, Rao, Mangala

Journal:

Journal of Immunological Methods

Year:

2017

Language:

english

File:

PDF, 5.36 MB

english, 2017

23

Immunokinetics of autoreactive CD4 T cells in blood: a reporter for the “hit-and-run” autoimmune attack on pancreas and diabetes progression

Sunil K. George, Ioana Preda, Serine Avagyan, Robert C. McEvoy, Robert Rapaport, Teodor-Doru Brumeanu, Sofia Casares

Journal:

Journal of Autoimmunity

Year:

2004

Language:

english

File:

PDF, 429 KB

english, 2004

24

Somatic genomic instability at microsatellites: A persistent and early event in cancer of the recessive mutator phenotype

Perucho, Manuel, Casares, Sofia, Ionov, Yurij, Malkhosyan, Sergei, Shibata, Darryl, Stanbridge, Eric

Journal:

Pathophysiology

Year:

1994

Language:

english

File:

PDF, 107 KB

english, 1994

25

02-P007 Drosophila viriato/Nol12, a novel Myc target gene, regulates nucleolar structure and composition and is required for cell proliferation and survival during development

Joana Marinho, Sofia Pinho, Inês Barbosa, Fernando Casares, Paulo Pereira

Journal:

Mechanisms of Development

Year:

2009

Language:

english

File:

PDF, 47 KB

english, 2009

26

Generation and testing anti-influenza human monoclonal antibodies in a new humanized mouse model (DRAGA: HLA-A2. HLA-DR4. Rag1 KO. IL-2Rγc KO. NOD)

Mendoza, Mirian, Ballesteros, Angela, Qi, Qiu, Sang, Luis Pow, Shashikumar, Soumya, Casares, Sofia, Brumeanu, Teodor-D.

Journal:

Human Vaccines & Immunotherapeutics

Year:

2017

Language:

english

File:

PDF, 1.09 MB

english, 2017

27

Soluble, dimeric HLA DR4-peptide chimeras: An approach for detection and immunoregulation of human type-1 diabetes

Ioana Preda, Robert C. McEvoy, Marvin Lin, Constantin A. Bona, Robert Rapaport, Teodor D. Brumeanu, Sofia Casares

Journal:

European Journal of Immunology

Year:

2005

Language:

english

File:

PDF, 661 KB

english, 2005

28

HLA-DR*0401 expression in the NOD mice prevents the development of autoimmune diabetes by multiple alterations in the T-cell compartment

Pow Sang, Luis, Surls, Jacqueline, Mendoza, Mirian, Casares, Sofia, Brumeanu, Teodor

Journal:

Cellular Immunology

Year:

2015

Language:

english

File:

PDF, 2.77 MB

english, 2015

29

The humanized DRAGA mouse (HLA-A2. HLA-DR4. RAG1 KO. IL-2R g c KO. NOD) establishes inducible and transmissible models for influenza type A infections

Mendoza, Mirian, Gunasekera, Devi, Pratt, Kathleen P., Qiu, Qi, Casares, Sofia, Brumeanu, Teodor-D.

Journal:

Human Vaccines & Immunotherapeutics

Year:

2020

File:

PDF, 3.66 MB

2020

30

T-cell Tolerance and Autoimmune Diabetes

Brumeanu, Teodor-Doru, Bona, Constants A., Casares, Sofia

Journal:

International Reviews Of Immunology

Year:

2001

Language:

english

File:

PDF, 1.77 MB

english, 2001

31

Analysis of lipid rafts in T cells

Sunil Thomas, Anca Preda-Pais, Sofia Casares, Teodor-D Brumeanu

Journal:

Molecular Immunology

Year:

2004

Language:

english

File:

PDF, 369 KB

english, 2004

32

Differential effect of CD4+Foxp3+ T-regulatory cells on the B and T helper cell responses to influenza virus vaccination

Jacqueline Surls, Cristina Nazarov-Stoica, Margaret Kehl, Sofia Casares, Teodor-D. Brumeanu

Journal:

Year:

2010

Language:

english

File:

PDF, 1.62 MB

english, 2010

33

Lymphokine-activated killer cytotoxicity and lymphocyte subpopulations in patients with acute leukemia

Antonio Parrado, Sofia Casares, Juan-Manuel Rodriguez-Fernandez

Journal:

Leukemia Research

Year:

1994

Language:

english

File:

PDF, 691 KB

english, 1994

34

Humanized DRAGA mice immunized with Plasmodium falciparum sporozoites and chloroquine elicit protective pre-erythrocytic immunity

Majji, Sai, Wijayalath, Wathsala, Shashikumar, Soumya, Brumeanu, Teodor D., Casares, Sofia

Journal:

Malaria Journal

Year:

2018

Language:

english

File:

PDF, 2.02 MB

english, 2018

35

Nonobese Diabetic (NOD) Mice Lack a Protective B-Cell Response against the “Nonlethal” Plasmodium yoelii 17XNL Malaria Protozoan

Mendoza, Mirian, Pow Sang, Luis, Qiu, Qi, Casares, Sofia, Brumeanu, Teodor-D.

Journal:

Malaria Research and Treatment

Year:

2016

Language:

english

File:

PDF, 2.26 MB

english, 2016

36

Rearrangement of the N-myc oncogene in acute leukemias: A case report

Sofía Casares, Juan Manuel Rodriguez, Antonio Martin, Antonio Parrado

Journal:

Leukemia Research

Year:

1993

Language:

english

File:

PDF, 670 KB

english, 1993

37

The RTS,S malaria vaccine

Sofia Casares, Teodor-Doru Brumeanu, Thomas L. Richie

Journal:

Year:

2010

Language:

english

File:

PDF, 585 KB

english, 2010

38

Modulation of CD4 T cell function by soluble MHC II-peptide chimeras

Casares, Sofia, Bona, Constantin A., Brumeanu, Teodor-Doru

Journal:

International Reviews Of Immunology

Year:

2001

Language:

english

File:

PDF, 1.53 MB

english, 2001

39

Induction of Antibody Response by DNA Immunization of Newborn Baboons Against Influenza Virus

BOT, ADRIAN, SHEARER, MICHAEL, BOT, SIMONA, WOODS, CATHERINE, LIMMER, JOERG, KENNEDY, RONALD, CASARES, SOFIA, BONA, CONSTANTIN

Journal:

Viral Immunology

Year:

1999

Language:

english

File:

PDF, 612 KB

english, 1999

40

Differential effect of HLA class-I versus class-II transgenes on human T and B cell reconstitution and function in NRG mice

Majji, Sai, Wijayalath, Wathsala, Shashikumar, Soumya, Pow-Sang, Luis, Villasante, Eileen, Brumeanu, Teodor D., Casares, Sofia

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.67 MB

english, 2016

41

Natural killer cytotoxicity and lymphocyte subpopulations in patients with acute leukemia

Antonio Parrado, Sofía Casares, Juan-Manuel Rodríguez-Fernández

Journal:

Leukemia Research

Year:

1994

Language:

english

File:

PDF, 506 KB

english, 1994

42

Antigen Presentation by Dendritic Cells after Immunization with DNA Encoding a Major Histocompatibility Complex Class IIârestricted Viral Epitope

Casares, Sofia, Inaba, Kayo, Brumeanu, Teodor-Doru, Steinman, Ralph M., Bona, Constantin A.

Journal:

Journal of Experimental Medicine

Year:

1997

File:

PDF, 158 KB

1997

43

Immunopotency of a viral peptide assembled on the carbohydrate moieties of self immunoglobulins

Brumeanu, Teodor-D., Casares, Sofia, Harris, Paul E., Dehazya, Philip, Wolf, Imre, Boehmer, Harold von, Bona, Constantin A.

Journal:

Nature Biotechnology

Year:

1996

File:

PDF, 517 KB

1996

44

Improvements and Limitations of Humanized Mouse Models for HIV Research: NIH/NIAID “Meet the Experts” 2015 Workshop Summary

Akkina, Ramesh, Allam, Atef, Balazs, Alejandro B., Blankson, Joel N., Burnett, John C., Casares, Sofia, Garcia, J. Victor, Hasenkrug, Kim J., Kashanchi, Fatah, Kitchen, Scott G., Klein, Florian, Kumar

Journal:

AIDS Research and Human Retroviruses

Year:

2016

Language:

english

File:

PDF, 250 KB

english, 2016

45

Double Negative (CD3+4−8−) TCRαβ Splenic Cells from Young NOD Mice Provide Long-Lasting Protection against Type 1 Diabetes

Duncan, Beverly, Nazarov–Stoica, Cristina, Surls, Jacqueline, Kehl, Margaret, Bona, Constantin, Casares, Sofia, Brumeanu, Teodor-D., Unutmaz, Derya

Journal:

Year:

2010

Language:

english

File:

PDF, 1.04 MB

english, 2010

46

Long-term silencing of autoimmune diabetes and improved life expectancy by a soluble pHLA-DR4 chimera in a newly-humanized NOD/DR4/B7 mouse

Pow Sang, Luis, Majji, Sai, Casares, Sofia, Brumeanu, Teodor D

Journal:

Human Vaccines & Immunotherapeutics

Year:

2014

Language:

english

File:

PDF, 1.76 MB

english, 2014

47

Escape from Self-tolerance Leads to Neonatal Insulin-dependent Diabetes Mellitus

Radu, Dorel L., Brumeanu, Teodor-Doru, McEvoy, Robert C., Bona, Constantin A., Casares, Sofia

Journal:

Year:

1999

Language:

english

File:

PDF, 521 KB

english, 1999

48

Pituitary neuroendocrine tumors (PitNETs): nomenclature evolution, not clinical revolution

Asa, Sylvia L., Asioli, Sofia, Bozkurt, Suheyla, Casar-Borota, Olivera, Chinezu, Laura, Comunoglu, Nil, Cossu, Giulia, Cusimano, Michael, Delgrange, Etienne, Earls, Peter, Ezzat, Shereen, Gazioglu, Nu

Journal:

Year:

2019

File:

PDF, 407 KB

2019

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